
Epitope Mapping
High-Resolution Insights for Immune Research & Diagnostics
Epitope mapping is a powerful way to analyse how antibodies recognize specific regions (epitopes) on proteins and pathogens.
By pinpointing these binding sites, researchers gain a deeper understanding of immune responses, guiding innovation in drug development, diagnostic research, and beyond.
Why Epitope Mapping Matters
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Identify Immunogenic Regions: Pinpoint sites targeted by anti-drug or autoantibodies, helping to mitigate adverse effects and optimize therapeutic design.
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Serological Profiling: Uncover pathogen-specific or auto-reactive antibody patterns in infectious diseases and immune disorders.
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Reveal Diagnostic Insights: Discover novel biomarkers or track disease progression through precise antibody-epitope interactions.
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Enhance Antibody Reliability: Validate the binding specificity of commercial or recombinant antibodies, confirming findings and increasing reliability.
Applications

Biologics Development
Minimize immunogenicity risks and refine therapeutic proteins.
Vaccine & Diagnostic Research
Assess vaccine response, characterize autoantibodies, and investigate infection responses.
Antibody Validation
Ensure reagents bind accurately to intended targets, preventing flawed data.
Autoimmune Disease
Characterise autoantibody profiles and disease mechanisms in complex conditions.
Core Capabilities
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Epitope mapping on high-density peptide microarrays
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Customizable arrays from protein, viral, or bacterial sequences
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Up to 100,000 peptides for comprehensive epitope discovery
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Standard arrays of ~1200 peptides for focused screening
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Expertise in immunology and antibody characterisation
Tailored Solutions
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Study design, immunological analysis & guidance
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Fully customizable peptide selection
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Bioinformatics & AI-guided epitope prediction
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Discovery confirmation via targeted immunoassay
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Peptide-ELISA diagnostic prototyping
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Custom peptide design & synthesis
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Ongoing technical and consultative support
Antibody Profiling
Immunoglobulins and Isotypes
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IgG (total) and/or subclasses 1-4
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IgM, IgA, IgE, IgD
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Non-human antibodies
Motif Discovery and Specificity
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Monoclonal antibody specificity
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Polyclonal antibody profiling
Assay Requirements
Sample Types
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Serum, plasma, dried blood spot
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Saliva
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Cell culture supernatant
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and more...
Minimal sample
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<20 µL per assay
Analysis & Bioinformatics
Robust, Quality-First Approach
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World-class immunology
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Microarray design from sequence
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AI-guided epitope prediction
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Data standardisation
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Integrated quality control targets
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Robust statistical analysis